Blar i forfatter "Dalton, R. Neil"

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    • Performance of creatinine-based equations to estimate glomerular filtration rate with a methodology adapted to the context of drug dosage adjustment 

      Delanaye, Pierre; Björk, Jonas; Courbebaisse, Marie; Couzi, Lionel; Ebert, Natalie; Eriksen, Bjørn Odvar; Dalton, R. Neil; Dubourg, Laurence; Melsom, Toralf; Nyman, Ulf (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-28)
      <p><i>Aim:</i> The Cockcroft-Gault (CG) creatinine-based equation is still used to estimate glomerular filtration rate (eGFR) for drug dosage adjustment. Incorrect eGFR may lead to hazardous over- or underdosing. <p><i>Methods:</i> In a cross-sectional analysis, CG was validated against measured GFR (mGFR) in 14 804 participants and compared with the Modification-of-Diet-in-Renal-Diseases (MDRD), ...

    • Prospects for improved glomerular filtration rate estimation based on creatinine-results from a transnational multicentre study 

      Bjõrk, Jonas; Nyman, Ulf; Courbebaisse, Marie; Couzi, Lionel; Dalton, R. Neil; Dubourg, Laurence; Ebert, Natalie; Eriksen, Bjõrn O.; Gaillard, Francois; Garrouste, Cyril; Grubb, Anders; Hansson, Magnus; Jacquemont1, Lola; Jones, Ian; Kamar, Nassim; Lamb, Edmund J.; Legendre, Christophe; Littmann, Karin; Mariat, Christophe; Melsom, Toralf; Rostaing, Lionel; Rule, Andrew D.; Schaeffner, Elke; Sundin, Per-Ola; Turner, Stephen; Åkesson, Anna; Delanaye, Pierre; Pottel, Hans (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-13)
      Background - The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) creatinine equation is routinely used to assess renal function but exhibits varying accuracy depending on patient characteristics and clinical presentation. The overall aim of the present study was to assess if and to what extent glomerular filtration rate (GFR) estimation based on creatinine can be improved.<p> <p>Methods ...